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Journal articles
Open Access
Monitoring our progress toward sustainability - desirable or undesirable?, TAPPI JOURNAL, May 1997, Vol. 80(5)

Monitoring our progress toward sustainability - desirable or undesirable?, TAPPI JOURNAL, May 1997, Vol. 80(5)

Journal articles
Open Access
Achieving compliance with 112(r): The road to success, TAPPI JOURNAL, May 1997, Vol. 80(5)

Achieving compliance with 112(r): The road to success, TAPPI JOURNAL, May 1997, Vol. 80(5)

Journal articles
Open Access
Pick the perfect thermoplastic for pulp and paper pipes and vessels, TAPPI JOURNAL, November 1997, Vol. 80(11)

Pick the perfect thermoplastic for pulp and paper pipes and vessels, TAPPI JOURNAL, November 1997, Vol. 80(11)

Journal articles
Open Access
Economic stability bodes well for Brazilian pulp and paper producers, TAPPI JOURNAL, November 1997, Vol. 80(11)

Economic stability bodes well for brazilian pulp and paper producers, TAPPI JOURNAL, November 1997, Vol. 80(11)

Journal articles
Open Access
Repulping wet-strength paper, TAPPI JOURNAL, November 1997, Vol. 80(11)

Repulping wet-strength paper, TAPPI JOURNAL, November 1997, Vol. 80(11)

Journal articles
Open Access
Role of polymers in deinking mixed paper, TAPPI JOURNAL, November 1997, Vol. 80(11)

Role of polymers in deinking mixed paper, TAPPI JOURNAL, November 1997, Vol. 80(11)

Journal articles
Open Access
Sootblower optimization II: Deposit and sootblower interaction, TAPPI JOURNAL, November 1997, Vol. 80(11)

Sootblower optimization ii: deposit and sootblower interaction, TAPPI JOURNAL, November 1997, Vol. 80(11)

Journal articles
Open Access
A diffusion model for the impregnation of lignocellulosic materials, TAPPI JOURNAL, November 1997, Vol. 80(11)

A diffusion model for the impregnation of lignocellulosic materials, TAPPI JOURNAL, November 1997, Vol. 80(11)

Journal articles
Open Access
Performance parameters of oxygen delignification, TAPPI JOURNAL, October 1997, Vol. 80(10)

Performance parameters of oxygen delignification, TAPPI JOURNAL, October 1997, Vol. 80(10)

Journal articles
Magazine articles
Open Access
Evaluation of rice straw for purification of lovastatin, TAPPI Journal November 2021

ABSTRACT: Cholesterol synthesis in the human body can be catalyzed by the coenzyme HMG-CoA reductase, and lovastatin, a key enzyme inhibitor, can reduce hypercholesterolemia. Lovastatin can be obtained as a secondary metabolite of Aspergillus terreus ATCC 20542. In this study, rice straw of lignocellulose was used in aeration and agitation bath fermentation in a 1-L flask, and a maximal crude extraction rate of 473 mg/L lovastatin was obtained. The crude extract was treated with silica gel (230•400 mesh) column chromatography. Ethyl acetate/ethanol (95%) was used as the mobile phase, and isolation was performed through elution with various ethyl acetate/ethanol ratios. The highest production rate of 153 mg/L was achieved with ethyl acetate/ethanol in a ratio of 8:2. The lovastatin gained from the crude extract was added to 12 fractions treated with 0.001 N alkali, and acetone was then added. After 24 h of recrystallization at 4°C, the extract underwent high-performance liquid chromatography. The purity had increased from 25% to 84.6%, and the recovery rate was 65.2%.

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