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Journal articles
Magazine articles
Open Access
Evaluation of rice straw for purification of lovastatin, TAPPI Journal November 2021

ABSTRACT: Cholesterol synthesis in the human body can be catalyzed by the coenzyme HMG-CoA reductase, and lovastatin, a key enzyme inhibitor, can reduce hypercholesterolemia. Lovastatin can be obtained as a secondary metabolite of Aspergillus terreus ATCC 20542. In this study, rice straw of lignocellulose was used in aeration and agitation bath fermentation in a 1-L flask, and a maximal crude extraction rate of 473 mg/L lovastatin was obtained. The crude extract was treated with silica gel (230–400 mesh) column chromatography. Ethyl acetate/ethanol (95%) was used as the mobile phase, and isolation was performed through elution with various ethyl acetate/ethanol ratios. The highest production rate of 153 mg/L was achieved with ethyl acetate/ethanol in a ratio of 8:2. The lovastatin gained from the crude extract was added to 12 fractions treated with 0.001 N alkali, and acetone was then added. After 24 h of recrystallization at 4°C, the extract underwent high-performance liquid chromatography. The purity had increased from 25% to 84.6%, and the recovery rate was 65.2%.

Journal articles
Open Access
Extended usage of xylanase enzyme to enhance the bleaching of softwood kraft pulp, TAPPI JOURNAL, January 2006

Extended usage of xylanase enzyme to enhance the bleaching of softwood kraft pulp, TAPPI JOURNAL, January 2006, Vol. 5(1) (164 KB)

Journal articles
Open Access
Comparative annual cost efficiency between thermal and chemical oxidation of TRS in kraft mills, TAPPI JOURNAL, July 2005, Vol. 4(7) (200 KB)

Comparative annual cost efficiency between thermal and chemical oxidation of TRS in kraft mills, TAPPI JOURNAL, July 2005, Vol. 4(7) (200 KB)

Journal articles
Open Access
Influence of kraft pulping on the kinetics of oxygen delignification, TAPPI JOURNAL, February 2000, Vol. 83(2)

Influence of kraft pulping on the kinetics of oxygen delignification, TAPPI JOURNAL, February 2000, Vol. 83(2)

Journal articles
Open Access
Direct causticization of kraft black liquor solids with tio2 in a fluidized bed, TAPPI JOURNAL, December 2000, Vol. 83(12)

Direct causticization of kraft black liquor solids with tio2 in a fluidized bed, TAPPI JOURNAL, December 2000, Vol. 83(12)

Journal articles
Open Access
Biological destruction of haps for cluster rule compliance, TAPPI JOURNAL, December 2000, Vol. 83(12)

Biological destruction of haps for cluster rule compliance, TAPPI JOURNAL, December 2000, Vol. 83(12)

Journal articles
Open Access
An engineered approach to paper and print improvement, TAPPI JOURNAL, December 2000, Vol. 83(12)

An engineered approach to paper and print improvement, TAPPI JOURNAL, December 2000, Vol. 83(12)

Journal articles
Open Access
Deinking of newspaper assisted by steam explosion, TAPPI JOURNAL, December 2000, Vol. 83(12)

Deinking of newspaper assisted by steam explosion, TAPPI JOURNAL, December 2000, Vol. 83(12)

Journal articles
Open Access
Calcium in pulping and bleaching, TAPPI JOURNAL, December 2000, Vol. 83(12)

Calcium in pulping and bleaching, TAPPI JOURNAL, December 2000, Vol. 83(12)

Journal articles
Open Access
A virtuous circle, TAPPI JOURNAL, December 2000, Vol. 83(12)

A virtuous circle, TAPPI JOURNAL, December 2000, Vol. 83(12)

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