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Evaluation of rice straw for purification of lovastatin, TAPPI Journal November 2021
ABSTRACT: Cholesterol synthesis in the human body can be catalyzed by the coenzyme HMG-CoA reductase, and lovastatin, a key enzyme inhibitor, can reduce hypercholesterolemia. Lovastatin can be obtained as a secondary metabolite of Aspergillus terreus ATCC 20542. In this study, rice straw of lignocellulose was used in aeration and agitation bath fermentation in a 1-L flask, and a maximal crude extraction rate of 473 mg/L lovastatin was obtained. The crude extract was treated with silica gel (230•400 mesh) column chromatography. Ethyl acetate/ethanol (95%) was used as the mobile phase, and isolation was performed through elution with various ethyl acetate/ethanol ratios. The highest production rate of 153 mg/L was achieved with ethyl acetate/ethanol in a ratio of 8:2. The lovastatin gained from the crude extract was added to 12 fractions treated with 0.001 N alkali, and acetone was then added. After 24 h of recrystallization at 4°C, the extract underwent high-performance liquid chromatography. The purity had increased from 25% to 84.6%, and the recovery rate was 65.2%.
Journal articles
Magazine articles
Control of malodorous gases emission from wet-end white water with hydrogen peroxide, TAPPI Journal October 2021
ABSTRACT: White water is highly recycled in the papermaking process so that its quality is easily deteriorated, thus producing lots of malodorous gases that are extremely harmful to human health and the environment. In this paper, the effect of hydrogen peroxide (H2O2) on the control of malodorous gases released from white water was investigated. The results showed that the released amount of total volatile organic compounds (TVOC) decreased gradually with the increase of H2O2 dosage. Specifically, the TVOC emission reached the minimum as the H2O2 dosage was 1.5 mmol/L, and meanwhile, the hydrogen sulfide (H2S) and ammonia (NH3) were almost completely removed. It was also found that pH had little effect on the release of TVOC as H2O2 was added, but it evidently affect-ed the release of H2S and NH3. When the pH value of the white water was changed to 4.0 or 9.0, the emission of TVOC decreased slightly, while both H2S and NH3 were completely removed in both cases. The ferrous ions (Fe2+) and the copper ions (Cu2+) were found to promote the generation of hydroxyl radicals (HOœ) out of H2O2, enhancing its inhibition on the release of malodorous gases from white water. The Fe2+/H2O2 system and Cu2+/H2O2 system exhibited similar efficiency in inhibiting the TVOC releasing, whereas the Cu2+/H2O2 system showed better perfor-mance in removing H2S and NH3.
Magazine articles
Capital cost analysis looks at recent and future trends, TAPPI JOURNAL, November 1992, Vol. 75(11)
Capital cost analysis looks at recent and future trends, TAPPI JOURNAL, November 1992, Vol. 75(11)
Magazine articles
Unbleached denim finds new life in 'blue jean' paper products, TAPPI JOURNAL, December 1993, Vol. 76(12)
Unbleached denim finds new life in 'blue jean' paper products, TAPPI JOURNAL, December 1993, Vol. 76(12)
Magazine articles
1994 polymers, laminations and coatings conference highlights technology basics, TAPPI JOURNAL, December 1994, Vol. 77(12)
1994 polymers, laminations and coatings conference highlights technology basics, TAPPI JOURNAL, December 1994, Vol. 77(12)
Magazine articles
Extend the life of your hoists, TAPPI JOURNAL, February 1994, Vol. 77(2)
Extend the life of your hoists, TAPPI JOURNAL, February 1994, Vol. 77(2)
Magazine articles
Chemical recovery conference emphasizes high solids firing and mill system closure, TAPPI JOURNAL, August 1995, Vol. 78(8)
Chemical recovery conference emphasizes high solids firing and mill system closure, TAPPI JOURNAL, August 1995, Vol. 78(8)
Magazine articles
Drying: New lime mud dryer kiln helps James Riverâ??s Pennington, AL, mill meet environmental restrictions, December 1995 Tappi Journal [95Dec37.pdf]
New lime mud dryer kiln helps james river's pennington, al, mill meet environmental restrictions, TAPPI JOURNAL, December 1995, Vol. 78(12)
Magazine articles
ECF results please gruvon mill, TAPPI JOURNAL, January 1995, Vol. 78(1)
ECF results please gruvon mill, TAPPI JOURNAL, January 1995, Vol. 78(1)
Magazine articles
Shop talk: reducing voc emissions with thermal oxidation units, TAPPI JOURNAL, December 1997, Vol. 80(12)
Shop talk: reducing voc emissions with thermal oxidation units, TAPPI JOURNAL, December 1997, Vol. 80(12)