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Magazine articles
Evaluation of rice straw for purification of lovastatin, TAPPI Journal November 2021
ABSTRACT: Cholesterol synthesis in the human body can be catalyzed by the coenzyme HMG-CoA reductase, and lovastatin, a key enzyme inhibitor, can reduce hypercholesterolemia. Lovastatin can be obtained as a secondary metabolite of Aspergillus terreus ATCC 20542. In this study, rice straw of lignocellulose was used in aeration and agitation bath fermentation in a 1-L flask, and a maximal crude extraction rate of 473 mg/L lovastatin was obtained. The crude extract was treated with silica gel (230–400 mesh) column chromatography. Ethyl acetate/ethanol (95%) was used as the mobile phase, and isolation was performed through elution with various ethyl acetate/ethanol ratios. The highest production rate of 153 mg/L was achieved with ethyl acetate/ethanol in a ratio of 8:2. The lovastatin gained from the crude extract was added to 12 fractions treated with 0.001 N alkali, and acetone was then added. After 24 h of recrystallization at 4°C, the extract underwent high-performance liquid chromatography. The purity had increased from 25% to 84.6%, and the recovery rate was 65.2%.
Magazine articles
Calcium based sulfur recovery process for kraft black liquor gasification - proof of concept', TAPPI JOURNAL, July 2000, Vol. 83(7)
Calcium based sulfur recovery process for kraft black liquor gasification - proof of concept', TAPPI JOURNAL, July 2000, Vol. 83(7)
Magazine articles
Taiwan holds first symposium on environmentally friendly and emerging technologies for a sustainable industry, TAPPI JOURNAL, September 2000, Vol. 83(9)
Taiwan holds first symposium on environmentally friendly and emerging technologies for a sustainable industry, TAPPI JOURNAL, September 2000, Vol. 83(9)
Magazine articles
The r & t system: everyone is responsible for innovation, TAPPI JOURNAL, September 2000, Vol. 83(9)
The r & t system: everyone is responsible for innovation, TAPPI JOURNAL, September 2000, Vol. 83(9)
Magazine articles
The role of science in setting the environmental agenda, TAPPI JOURNAL, September 2000, Vol. 83(9)
The role of science in setting the environmental agenda, TAPPI JOURNAL, September 2000, Vol. 83(9)
Magazine articles
A financial analysis of north american pulp and paper companies, TAPPI JOURNAL, July 2000, Vol. 83(7)
A financial analysis of north american pulp and paper companies, TAPPI JOURNAL, July 2000, Vol. 83(7)
Magazine articles
Annual chip excellence award recognizes suppliers, TAPPI JOURNAL, November 2000, Vol. 83(11)
Annual chip excellence award recognizes suppliers, TAPPI JOURNAL, November 2000, Vol. 83(11)
Magazine articles
Pitfalls of trading market pulp on the internet, TAPPI JOURNAL, November 2000, Vol. 83(11)
Pitfalls of trading market pulp on the internet, TAPPI JOURNAL, November 2000, Vol. 83(11)
Magazine articles
Health check: market pulp, TAPPI JOURNAL, November 2000, Vol. 83(11)
Health check: market pulp, TAPPI JOURNAL, November 2000, Vol. 83(11)
Magazine articles
The r & t system: everyone is responsible for innovation, TAPPI JOURNAL, September 2000, Vol. 83(9)
The r & t system: everyone is responsible for innovation, TAPPI JOURNAL, September 2000, Vol. 83(9)